发明名称 Device for detecting and separating target molecules and method for detecting and separating target molecules by using the same
摘要 A device, system, and method for detecting or separating target molecules allowing efficient detection even when only a small amount of target molecules or target cells are included in a sample involving the use of a target molecule linkage portion, a signal production portion, and first and second separation portions.
申请公布号 US8753870(B2) 申请公布日期 2014.06.17
申请号 US201213605787 申请日期 2012.09.06
申请人 Samsung Electronics Co., Ltd.;Industry -University Coorperation Foundation Sogang University 发明人 Lee Hun-joo;Lee Jeong-gun;Choi Jeong-woo;Kim Yeon-jeong;Park Jong-myeon;Song Mi-jeong;Oh Jin-mi
分类号 C12M1/00;C12Q1/68;G01N33/53;C12M1/34;C12M3/00;G01N30/96;C07H21/02 主分类号 C12M1/00
代理机构 Leydig, Voit & Mayer, Ltd. 代理人 Leydig, Voit & Mayer, Ltd.
主权项 1. A device for detecting or separating target molecules, the device comprising: a target molecule linkage portion that is specifically linkable to a target molecule; a signal production portion that is linked to the target molecule linkage portion and produces a detectable signal; a first separation portion linked to the signal production portion; and a second separation portion that is fixed on a solid support and is specifically linkable to the first separation portion, wherein the first separation portion and the second separation portion have an enzyme cleavage region when linked to each other and configured to release the signal production portion, target molecule linkage portion, and any linked target molecule from the support upon cleavage by an enzyme; wherein the first separation portion and second separation portion are between the solid support and the signal production portion, and the signal production portion is between the first separation portion and the target molecule linkage portion.
地址 Suwon-Si KR