Methods, kits and compositions pertaining to the suppression of the detectable probe binding to randomly distributed repeat sequences genomic nucleic acid

摘要

This invention is directed to methods, kits, non-nucleotide probes as well as other compositions pertaining to the suppression of binding of detectable nucleic acid probes to undesired nucleotide sequences of genomic nucleic acid in assays designed to determine target genomic nucleic acid.

主权项

1. A mixture of non-nucleotide probes, the probes comprising a nucleobase sequence identical to each of the nucleobase sequences of the group consisting of: Seq. Id. No. 3, Seq. Id. No. 4, Seq. Id. No. 5, Seq. Id. No. 6, Seq. Id. No. 7, Seq. Id. No. 8, Seq. Id. No. 9, Seq. Id. No. 10, Seq. Id. No. 11, Seq. Id. No. 12, Seq. Id. No. 13, and TT(k)TTTTT(k)TTTLysOLysOTTT(k)TTTTT(k)TT, wherein (k) is a D-lysine, Lys is L-lysine, and O is 8-amino-3,6-dioxaoctanoic acid.