| 发明名称 |
USE OF MUTANT HERPES SIMPLEX VIRUS-2 FOR CANCER THERAPY |
| 摘要 |
<p>The present invention is directed to the composition and use of a modified Herpes Simplex Virus Type 2 (HSV-2) as a medicament in the treatment of cancer. The modified HSV-2 has fusogenic activity, and comprises a modified/mutated ICP10 polynucleotide encoding a polypeptide having ribonucleotide reductase activity and lacking protein kinase activity.</p> |
| 申请公布号 |
CA2613310(C) |
申请公布日期 |
2014.06.17 |
| 申请号 |
CA20062613310 |
申请日期 |
2006.06.23 |
| 申请人 |
BAYLOR COLLEGE OF MEDICINE |
发明人 |
ZHANG, XIAOLIU;FU, XINPING |
| 分类号 |
A61K48/00 |
主分类号 |
A61K48/00 |
| 代理机构 |
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