Tissue resection device and method

摘要

Among other things, embodiments of devices (and parts thereof) are disclosed that can be used in treating Barrett's esophagus. Embodiments may have a suction cavity or window portion having elongated planar floor and ramped end surfaces with suction holes on one or both end surfaces. Examples include one or more fluid injection needles and parts for controlling fluid injection rate based on the rate of needle withdrawal. Embodiments can include one or more injection needles and receiving holes, with the ability to allow injectate to flow into tissue before withdrawing the needle(s), and/or lockout mechanism to prevent resection of tissue by a cutting mechanism prior to injection of fluid. Methods for treatment are also disclosed, and can include inserting a needle completely through tissue, and injecting fluid into tissue while withdrawing the needle back through the tissue, and/or injecting fluid into tissue while moving the needle forward through tissue.

主权项

1. A device for treating Barrett's esophagus, comprising:
a shaft having a working end with a window portion for accepting mucosal tissue of a patient's esophagus, a suction lumen extending from a first proximal opening to the working end, and a guiding lumen extending from a second proximal opening to the working end, wherein the window portion includes a floor surface, oblique proximal and distal surfaces and side surfaces, a plurality of needles extending from or through the floor surface and a plurality of suction openings through the floor surface and connected to the suction lumen; a cutting mechanism passing through the shaft, the cutting mechanism including a cutting blade, a handle and a force transmitting portion, the force transmitting portion being movable through the shaft by operation of the handle, the cutting blade being movable through the window portion; a fluid injection system including a distal needle tip, a syringe, and a conduit connecting the syringe and the needle tip, wherein the syringe includes a barrel and plunger fitted into the barrel, wherein the syringe, conduit and needle tip are movable with respect to the shaft, so that movement of the syringe barrel distally pushes the needle tip along the shaft and through the window portion.