发明名称 Influenza vaccine
摘要 The present invention discloses isolated peptides encoding an antigen or fragments thereof from the N-terminus of hemagglutinin protein of influenza, methods for isolating such antigens and specific uses thereof. The peptide can be used as a vaccine to generate an antibody response that neutralizes influenza infectivity against a variety of influenza strains.
申请公布号 US8753623(B2) 申请公布日期 2014.06.17
申请号 US201013266801 申请日期 2010.04.29
申请人 发明人 He Runtao;Li Xuguang;Van Domselaar Gary
分类号 A61K39/145;G01K7/08;C12Q1/70;C07K16/10;C07K17/06;G01N33/569 主分类号 A61K39/145
代理机构 Ade & Company Inc. 代理人 Williams Michael R.;Ade & Company Inc.
主权项 1. A method of immunizing an individual against influenza virus comprising inducing a neutralizing immunity against influenza virus in said individual by administering to said individual an effective amount of a conjugate comprising a peptide consisting of the amino acid sequence as set forth in SEQ ID No. 6 connected by a linker to a carrier protein such that antibodies that interfere with an influenza virus replication are generated.
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