发明名称 |
Influenza vaccine |
摘要 |
The present invention discloses isolated peptides encoding an antigen or fragments thereof from the N-terminus of hemagglutinin protein of influenza, methods for isolating such antigens and specific uses thereof. The peptide can be used as a vaccine to generate an antibody response that neutralizes influenza infectivity against a variety of influenza strains. |
申请公布号 |
US8753623(B2) |
申请公布日期 |
2014.06.17 |
申请号 |
US201013266801 |
申请日期 |
2010.04.29 |
申请人 |
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发明人 |
He Runtao;Li Xuguang;Van Domselaar Gary |
分类号 |
A61K39/145;G01K7/08;C12Q1/70;C07K16/10;C07K17/06;G01N33/569 |
主分类号 |
A61K39/145 |
代理机构 |
Ade & Company Inc. |
代理人 |
Williams Michael R.;Ade & Company Inc. |
主权项 |
1. A method of immunizing an individual against influenza virus comprising inducing a neutralizing immunity against influenza virus in said individual by administering to said individual an effective amount of a conjugate comprising a peptide consisting of the amino acid sequence as set forth in SEQ ID No. 6 connected by a linker to a carrier protein such that antibodies that interfere with an influenza virus replication are generated.
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地址 |
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