Multi-way sorter system and method

摘要

Provided herein are improved multi-way cell sorter systems and methods. For example, provided are systems and methods for the collection of cells that are sorted in multiple directions. The systems and methods allow for the construction of a multi-way sorter (e.g., a ten-way sorter in the space that currently only allows four-way sorting). In addition the device may actively sense the arrival of drops (with cells of interest) at a sample tube, and trigger an alarm when the drops' arrivals deviate from an expected pattern.

主权项

1. A carrier for receiving cells sorted from a cell sorter system, the carrier comprising:
a plurality of hollow deflection tubes, wherein each deflection tube has a first opening at a first end and a second opening at a second end, wherein the first opening of each deflection tube is aligned with the first opening of an adjacent deflection tube such that the first openings are all collinear, and wherein the second openings of the plurality of deflection tubes are staggered with respect to one another; a plurality of collection tubes corresponding to the plurality of deflection tubes, wherein each collection tube includes an opening positioned to receive a cell passed through and exiting a corresponding deflection tube; and a current detection circuit coupled to at least one deflection tube.