Surface modified metal nano-particle and use thereof

摘要

The present invention provides a metal nanoparticle that is surface-modified with a hydrophilic or hydrophobic functional group, and a composition for optical detection comprising the same. The surface-modified nanoparticles according to the present invention form clusters suitable for optical detection, for example, suitable as an X-ray contrast agent, and have surface plasmon energy in the visible region, thereby being usefully applied to a variety of optical detection methods.

主权项

1. A method for optically detecting a biological sample using a surface-modified metal nanoparticle, the method comprising:
introducing a surface-modifying material to a metal nanoparticle; injecting a composition comprising the surface-modified metal nanoparticle into the biological sample; and detecting the biological sample by performing X-ray imaging, UV spectroscopy, or fluorescence analysis of the surface-modifying material of the surface-modified metal nanoparticle, wherein a particle diameter of the metal nanoparticle ranges from 10 to 30 nm, and wherein the surface-modifying material is mercaptoethanol.