发明名称 Alkylamido compounds and uses thereof
摘要 Disclosed herein are compounds that may be specific to PPAR and/or EGF receptors, and methods of making and using same.
申请公布号 US8754127(B2) 申请公布日期 2014.06.17
申请号 US201013201786 申请日期 2010.02.16
申请人 Nogra Pharma Limited 发明人 Baroni Sergio;Bellinvia Salvatore;Viti Francesca
分类号 A61K31/196;A61K31/216;C07C229/42 主分类号 A61K31/196
代理机构 Goodwin Procter LLP 代理人 Goodwin Procter LLP
主权项 1. A compound of formula I: wherein X is C1-C3alkylene, optionally substituted with one, two or three substituents selected from halogen or hydroxyl; R1 is selected from the group consisting of C1-C6alkyl, C3-C6cycloalkyl, C2-C6alkenyl, and C2-C6alkynyl; R2 is selected from the group consisting of hydrogen and C1-C6alkyl; R3 is independently selected, for each occurrence from the group consisting of hydrogen, C1-C6alkyl, cyano, C3-C6cycloalkyl, hydroxyl, and nitro; R4 is selected from the group consisting of hydrogen and C1-C6alkyl; R5 is hydrogen or C1-C6alkyl; or pharmaceutically acceptable salts or N-oxides thereof.
地址 Dublin IE