| 发明名称 | Gradient-elution multi-column separation method | ||
| 摘要 | The invention relates to a method for separating fractions of a mixture to be separated including the steps of providing a device comprising at least two chromatography columns mounted in series, discontinuously injecting a mixture to be separated, in a single point of the device, discontinuously drawing off the fraction enriched in the product of interest, in a single point of the device, and injecting eluents in each column and displacing the points for injection eluents, the eluents having a different eluting power. The method allows efficient separation which is simple to perform. | ||
| 申请公布号 | US8752417(B2) | 申请公布日期 | 2014.06.17 |
| 申请号 | US200912936319 | 申请日期 | 2009.04.03 |
| 申请人 | Novasep | 发明人 | Valery Eric;Osuna Sanchez Hector;Bailly Michel |
| 分类号 | G01N30/02 | 主分类号 | G01N30/02 |
| 代理机构 | Marsh Fischmann & Breyfogle LLP | 代理人 | Marsh Fischmann & Breyfogle LLP ;Szummy Jonathon A. |
| 主权项 | 1. A method for separating fractions of a mixture to be separated comprising the steps of providing a device comprising at least two chromatography columns mounted in series, discontinuously injecting a mixture to be separated, in a first single point of the device, discontinuously drawing off the fraction enriched in the product of interest, in a second single point of the device, and injecting eluents in a plurality of points of each column and displacing the plurality of points for injecting eluents, the eluents having a different eluting power. | ||
| 地址 | Pompey FR | ||