发明名称 |
POLYMERIC MICROPARTICLES CONTAINING A HYDROPHOBIC DRUG FOR SUSTAINED RELEASE THEREOF AND METHOD FOR PREPARING THE SAME |
摘要 |
The present invention relates to a sustained release microparticle containing a water soluble drug and to a manufacturing method thereof. The sustained release microparticle contains a water soluble drug and one among polylactic acid containing at least one carboxy group in the end and a multivalent metal cation salt of a derivative thereof. The present invention can continuously maintain a constant burst speed and an effective blood concentration without the rapidly excessive and delayed burst of the drug in the beginning since the water soluble drug is collected in the polylactic acid or the multivalent metal cation salt of the derivative thereof, thereby capable of being used as the sustained release preparation of the water soluble drug. |
申请公布号 |
KR20140072843(A) |
申请公布日期 |
2014.06.13 |
申请号 |
KR20140047890 |
申请日期 |
2014.04.22 |
申请人 |
SAMYANG BIOPHARMACEUTICALS CORPORATION |
发明人 |
LEE, SA WON;KIM, DO HOON;KIM, BONG O;SEO, MIN HYO |
分类号 |
A61K9/16;A61K9/22;A61K47/14;A61K47/36 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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