Preparing fluorinated compound, which is useful to prepare e.g. monofluoroacetic acid, difluoroacetic acid, and trifluoroacetic acid, comprises reacting organic compound with fluorine compound in presence of catalyst

摘要

Preparing fluorinated compound (I), comprises reacting an organic compound (II) with a fluorine compound (III) in the presence of a catalyst. Preparing fluorinated compound of formula (CA aH cX x - nF y + nT) (I), comprises reacting an organic compound of formula ((CA aH cX xF yU1)) (II) with a fluorine compound of formula (CD1 dH bZ zF wCOF) (III) in the presence of a catalyst. a, b, c, d, y, x-n : 0-2, where sum of a and c, and b and d is 0-2; x, n, y+n : 1-3, where sum of a, c, x, and y is 3; T : COF or S(O) 2F; U1 : COR or S(O) 2R; R : F (preferred), Cl, Br, or I; X, Z : Cl (preferred), Br, or I; z, w : 0-3, where sum of b, d, z and w is 3; and A, D1 : organic groups comprising at least one atom of C and H atoms, and optionally O or N. An independent claim is included for preparing a fluorine compound of formula (CA aH cX x - nF y + nW1) (Ia), comprising preparing (I), and then hydrolyzing (I). W1 : COOH or its salt or SO 2OH.