发明名称 |
P16INK4A DERIVED PEPTIDES FOR PROPHYLAXIS AND THERAPY OF HPV-ASSOCIATED TUMORS AND OTHER P16INK4A EXPRESSING TUMORS |
摘要 |
<p>Described are particular fragments of the cyclin-dependent kinase inhibitor p16 capable of increasing IFN-.gamma. secretion of T cells or inducing proliferation of T cells and the use of said fragments for immunizing an individual against HPV-associated or other p16 INK4a expressing carcinomas, preferably advanced carcinomas.</p> |
申请公布号 |
CA2799804(A1) |
申请公布日期 |
2014.06.13 |
申请号 |
CA20122799804 |
申请日期 |
2012.12.13 |
申请人 |
RUPRECHT-KARLS-UNIVERSITAT HEIDELBERG |
发明人 |
KLOOR, MATTHIAS;REUSCHENBACH, MIRIAM;VON KNEBEL-DOEBERITZ, MAGNUS |
分类号 |
C07K14/47;A61K39/00;A61P35/00;A61P37/04;C12N15/12;C12N15/86 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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