发明名称 |
MONOCLONAL ANTIBODIES WITH ENHANCED ADCC FUNCTION |
摘要 |
The invention concerns a method for obtaining and selecting monoclonal antibodies by an ADDC-type test, said antibodies capable of activating type III Fcy receptors and having a particular glycan structure. The inventive anti-D antibodies can be used for preventing Rhesus isoimmunisation in Rh negative persons, in particular for haemolytic disease in a new-born baby of for uses such as idiopathic thrombocytopenic pupura 9ITP) |
申请公布号 |
US2014162356(A1) |
申请公布日期 |
2014.06.12 |
申请号 |
US201414157061 |
申请日期 |
2014.01.16 |
申请人 |
LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES |
发明人 |
Beliard Roland;Bourel Dominique;Glacet Arnaud;De Romeuf Christophe;Bihoreau Nicolas;Nony Emmanuel |
分类号 |
C07K16/34 |
主分类号 |
C07K16/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Les Ulis FR |