发明名称 |
NOVEL SINGLE NUCLEOTIDE POLYMORPHISMS AND COMBINATIONS OF NOVEL AND KNOWN POLYMORPHISMS FOR DETERMINING THE ALLELE-SPECIFIC EXPRESSION OF THE IGF2 GENE |
摘要 |
Single nucleotide polymorphisms and uses for determining the imprinting status of the Insulin Growth Factor-2 gene in a clinical specimen are described. |
申请公布号 |
US2014162255(A1) |
申请公布日期 |
2014.06.12 |
申请号 |
US201313961794 |
申请日期 |
2013.08.07 |
申请人 |
Ordway Jared;Lakey Nathan;Maloney Rebecca;Rohlfing Theresa |
发明人 |
Ordway Jared;Lakey Nathan;Maloney Rebecca;Rohlfing Theresa |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
1. A method of quantifying allelic-specific expression of RNA in a human individual that is a heterozygote for a single nucleotide polymorphism (SNP) in the Insulin Growth Factor-2 (IGF2) gene, the method comprising
quantifying in a sample from the individual the amount of RNA comprising each polymorphic option of the SNP, wherein the SNP comprises SEQ ID NO: 16.
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地址 |
St. Louis MO US |