发明名称 |
MULTIFUNCTIONAL Fe3O4 CORED MAGNETIC-QUANTUM DOT FLUORESCENT NANOCOMPOSITES FOR RF NANO-HYPERTHERMIA OF CANCER CELLS |
摘要 |
A magnetic oxide-quantum dot nanocomposite has at least one magnetic oxide nanoparticle coated with a silica (SiO2) shell and terminated with at least one thiol group (—SH) and at least one CdSe/ZnS quantum dot linked with the at least one SiO2-coated magnetic oxide nanoparticle via the at least one thiol group. The at least one magnetic oxide nanoparticle can be an iron oxide (Fe3O4) nanoparticle. A method of cancer treatment using the magnetic oxide-quantum dot nanocomposites, includes the steps of delivering a plurality of nmagnetic oxide-quantum dot nanocomposites to a cancer cell, and subjecting the cancer cell with the plurality of magnetic oxide-quantum dot nanocomposites to a radio frequency induction for a period of time effective to cause the cancer cell to die. |
申请公布号 |
US2014161890(A1) |
申请公布日期 |
2014.06.12 |
申请号 |
US201414181981 |
申请日期 |
2014.02.17 |
申请人 |
Board of Trustees of the University of Arkansas |
发明人 |
Biris Alexandru S.;Xu Yang;Wang Daoyuan |
分类号 |
A61K41/00 |
主分类号 |
A61K41/00 |
代理机构 |
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代理人 |
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主权项 |
1. A magnetic oxide-quantum dot nanocomposite, comprising:
(a) at least one magnetic oxide nanoparticle coated with a silica (SiO2) shell and terminated with at least one thiol group (—SH); and (b) at least one CdSe/ZnS quantum dot linked with the at least one SiO2-coated magnetic oxide nanoparticle via the at least one thiol group.
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地址 |
Little Rock AR US |