| 发明名称 |
Antibody Specific for CD22 and Methods of Use Thereof |
| 摘要 |
The present disclosure provides antibodies specific for an epitope present on CD22. The antibodies are useful in various treatment, diagnostic, and monitoring applications, which are also provided. |
| 申请公布号 |
US2014161870(A1) |
申请公布日期 |
2014.06.12 |
| 申请号 |
US201313942140 |
申请日期 |
2013.07.15 |
| 申请人 |
REDWOOD BIOSCIENCE, INC. |
发明人 |
Rabuka David;Holgate Robert George Edward;Carr Francis Joseph |
| 分类号 |
C07K16/28;A61K47/48 |
主分类号 |
C07K16/28 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An antibody that specifically binds an epitope in CD22, wherein the antibody comprises:
a) an immunoglobulin heavy chain comprising a VH region having the amino acid sequence EVQLVESGGGLVKPGGSLX1LSCAASGFAFSIYDMSWVRQAPGKGLEWVAYISSGGGTTYYPD TVKGRFTISRDNAKNX2LYLQMX3SLRAEDTAMYYCARHSGYGSSYGVLFAYWGQGTLVTVSS (SEQ ID NO:1), where X1 is K or R; X2 is S or T; and X3 is N or S; and b) an immunoglobulin light chain.
|
| 地址 |
EMERYVILLE CA US |
