| 发明名称 |
ANTIBODY-ACTIVE AGENT CONJUGATES AND METHODS OF USE |
| 摘要 |
The invention provides protein-active agent conjugates having an amino acid motif that can be recognized by an isoprenoid transferase. The invention also provides compositions containing the conjugates. The invention further provides methods for using the conjugates to deliver the active agent to a target cell, as well as methods for using the conjugates to treat a subject in need thereof (e.g., a subject in need of the active agent). |
| 申请公布号 |
US2014161829(A1) |
申请公布日期 |
2014.06.12 |
| 申请号 |
US201414181648 |
申请日期 |
2014.02.15 |
| 申请人 |
LegoChem Biosciences, Inc. |
发明人 |
Kim Yongzu;Park Taekyo;Woo Sungho;Lee Hyangsook;Kim Sunyoung;Cho Jongun;Jung Doohwan;Kim Youngun;Kwon Hyunjin;Oh Kyuman;Chung Yunseo;Park Yun-Hee |
| 分类号 |
A61K47/48 |
主分类号 |
A61K47/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A protein-active agent conjugate comprising a protein having an amino acid motif that can be recognized by an isoprenoid transferase, wherein the active agent is covalently linked to the protein at the amino acid motif.
|
| 地址 |
Daejeon KR |
