METALLIC TITANIUM -BASED CARDIOVASCULAR STENT WITH NANO - STRUCTURED SURFACE AND METHOD OF MANUFACTURING THEREOF

摘要

A method of preparing bio-compatible metallic stents based on Titanium having a nano structured titania layer that promotes superior endothelialization, with simultaneous inhibition of smooth muscle cell proliferation and platelet adhesion for specific use in cardio vascular applications. The method of nano texturing of stents involves subjecting the metallic surface to hydo-thermal treatment in alkaline conditions at elevated temperatures. This invention describes a medical device which may be used as a vascular (stent, heart valves), or endotracheal or prostatic device.