INCREASED YIELDS OF BIOSYNTHESIZED PRODUCTS

摘要

The invention provides a non-naturally occurring microbial organism having a butadiene biosynthetic pathway, a denitrification enzyme or pathway for reducing nitrate (N03-) or nitrite (N02-) and a metabolic modification attenuating the amount or activity of a cytoplasmic nitrite reductase. Also provided is a composition including a non-naturally occurring microbial organism having a butadiene biosynthetic pathway, a denitrification enzyme or pathway for reducing nitrate (N03-) or nitrite (N02-) and a medium containing nitrate. Methods of producting bioderived butadiene are also provided.