| 发明名称 |
PROCESS FOR PRODUCING FLUORINATED ALCOHOLS |
| 摘要 |
The present invention is directed to a process for preparation of fluorinated alcohols of Formula (I);RfCH2CH2OH (I);by contacting a fluorinated iodide with an alkyl vinyl ether in the presence of an initiator and a base to generate an intermediate hemi-acetal or aldehyde or a mixture thereof, followed by hydrogenation of the hemi-acetal of Formula (II);RfCH2CH(OCxH2x+1)m(OH)p (II);or aldehyde of Formula (III);RfCH2CHO (III);or a mixture thereof, to yield a compound of Formula (I). |
| 申请公布号 |
US2014163262(A1) |
申请公布日期 |
2014.06.12 |
| 申请号 |
US201213706785 |
申请日期 |
2012.12.06 |
| 申请人 |
E I DU PONT DE NEMOURS AND COMPANY |
发明人 |
MOLOY KENNETH GENE;Peng Sheng |
| 分类号 |
C07C29/141;C07C29/132 |
主分类号 |
C07C29/141 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A process for preparation of a compound of Formula (I)
RfCH2CH2OH (I) wherein Rf is linear or branched CnF2n+1 optionally interrupted intermittently by at least one oxygen, CH2, or CH2CH2; and n is 1 to 10; comprising a) contacting a compound of formula RfI, wherein Rf is defined as above, with an alkyl vinyl ether containing 1 to 4 carbons in the alkyl, in the presence of an initiator and a base to generate an intermediate hemi-acetal of Formula (II) or aldehyde of Formula (III) or a mixture thereof
RfCH2CH(OCxH2x+1)m(OH)p (II)RfCH2CHO (III) wherein Rf is defined as above, m is 0 to 1; and p is 1 to 2; provided that m+p is 2; and x is 1 to 4; and b) hydrogenating the hemi-acetal of Formula (II) or aldehyde of Formula (III) or a mixture thereof to yield a compound of Formula (I).
|
| 地址 |
Wilmington DE US |
