发明名称 |
LM-antibodies, functional fragments, LM-1 target antigen, and methods for making and using same |
摘要 |
<p>The invention provides LM-1 antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions. The invention also provides antibodies, functional fragments, modified and variant forms that bind to LM-1 antigen (e.g., NONO/nmt55). Antibodies, functional fragments, modified and variant forms, nucleic acid and other compositions are useful in treatment and diagnostic methods. One method includes treating metastasis of a neoplasia, tumor or cancer in a subject in need of treatment by administering to the subject an amount of a LM-1 antibody, an antibody that binds to LM-1 antigen, or a functional fragment thereof, effective to treat metastasis of the neoplasia, tumor or cancer in the subject.</p> |
申请公布号 |
AU2009269704(B2) |
申请公布日期 |
2014.06.12 |
申请号 |
AU20090269704 |
申请日期 |
2009.06.15 |
申请人 |
PATRYS LIMITED |
发明人 |
KELTER, ARNDT-RENE;BRANDLEIN, STEPHANIE UTE;SCHOENEN, FRANK;UDABAGE, LISHANTHI;ILAG, LEODEVICO L.;HOSKING, CHRISTOPHER GARTH;POWER, BARBARA;HENSEL, FRANK;THALHEIMER, ANDREAS;VOLLMERS, HEINZ PETER |
分类号 |
C07K16/18;A61K39/395;A61P35/04;G01N33/563;G01N33/574 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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