摘要 |
The present invention provides systems, methods, and compositions for targeted delivery of nanoparticles and/or agents to tissues, cells, and/or subcellular locales. In general, compositions comprise a nanoparticle (e.g. quantum dot, polymeric particle, etc.), at least one modulating entity (such as a targeting moiety, transfection reagent, protective entity, etc.), and at least one agent to be delivered (e.g. therapeutic, prophylactic, and/or diagnostic agent). The present invention provides methods of making and using nanoparticle entities in accordance with the present invention. |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
AGRAWAL, AMIT;BHATIA, SANGEETA N.;DERFUS, AUSTIN M.;HARRIS, TODD;MIN, DAL-HEE;VON MALTZAHN, GEOFFREY |