Temotsolomidin polymeeripartikkelipohjainen annosmuoto pahanlaatuisten kasvainten hoitoon

摘要

The invention relates to pharmacology and medicine, and more specifically to slow-release antitumor drug composition based on biodegradable poly(lactic-co-glycolic acid) (PLGA). The composition comprises temozolomide (TMZ) as the active ingredient and comprises, in addition, surface-active material and a cryoprotectant as parts of nanoparticles.