MTOR kinase inhibitors for oncology indications and diseases associated with the MTOR/P13K/AKT pathway

摘要

Provided herein are Heteroaryl Compounds having the following structure:
wherein R 1 -R 3 are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and a Heteroaryl Compound provided herein for use in a method of treating or preventing cancer, inflammatory conditions, immunological conditions, neurodegenerative diseases, diabetes, obesity, neurological disorders, age-related diseases, or cardiovascular conditions, wherein the method comprising administering an effective amount of the Heteroaryl Compound to a patient in need thereof.