发明名称 |
Selective androgen receptor modulators (SARMs) and uses thereof |
摘要 |
Provided herein are compounds, such as compounds of Formula I, that bind to androgen receptors and/or modulate activity of androgen receptors. Also provided are methods for making and using such compounds. Also provided are compositions including such compounds and methods for making and using such compositions.; |
申请公布号 |
US8748633(B2) |
申请公布日期 |
2014.06.10 |
申请号 |
US201213694063 |
申请日期 |
2012.10.23 |
申请人 |
Ligand Pharmaceuticals Incorporated |
发明人 |
Zhi Lin |
分类号 |
C07D207/08 |
主分类号 |
C07D207/08 |
代理机构 |
|
代理人 |
|
主权项 |
1. A method for modulating an androgen receptor, comprising:
contacting an androgen receptor with a compound of formula I: wherein:
R1 is CF3, F or Cl;R2 is H or methyl; andR3 is H or methyl,or a pharmaceutically acceptable salt or ester thereof.
|
地址 |
La Jolla CA US |