发明名称 |
ANTI-FERROPORTIN 1 MONOCLONAL ANTIBODIES AND USES THEREOF |
摘要 |
Provided are monoclonal antibodies and antigen-binding fragments thereof that bind to, and inhibit the activity of human FPN1, and which are effective in maintaining or increasing the transport of iron out of mammalian cells and/or maintaining or increasing the level of serum iron, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a subject in vivo. |
申请公布号 |
CA2745618(C) |
申请公布日期 |
2014.06.10 |
申请号 |
CA20092745618 |
申请日期 |
2009.12.01 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
LEUNG, DONMIENNE DOEN MUN;LUAN, PENG;MANETTA, JOSEPH VINCENT;TANG, YING;WITCHER, DERRICK RYAN |
分类号 |
C07K16/28;A61K39/395;A61P7/06;C07K14/705;C12N15/13 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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