发明名称 COMPOSITIONS AND METHODS FOR IMPROVING SOMATOSTATIN IMMUNOGENICITY IN TREATING GROWTH HORMONE AND INSULIN-LIKE GROWTH FACTOR DEFICIENCY
摘要 FIELD: medicine.SUBSTANCE: group of inventions refers to medicine and concerns methods of treating growth hormone or insulin-like growth factor 1 deficiency in a patient involving administering an immunogenic amount of a vaccine containing a chimeric somatostatin-14 based polypeptide bound to inactivated chloramphenicol acetyltransferase (CAT), and an adjuvant; the vaccine for treating the patient having growth hormone or insulin-like growth factor 1 deficiency; a method of treating obesity in the patient involving administering the immunogenic amount of the vaccine.EFFECT: group of inventions provide the immunogenicity for somatostatin and higher release of endogenously produced growth hormone and/or insulin-like growth factor 1.22 cl, 8 ex, 6 dwg, 2 tbl
申请公布号 RU2519051(C2) 申请公布日期 2014.06.10
申请号 RU20110100105 申请日期 2009.06.24
申请人 BRAASH BIOTEKH LLK 发明人 KEJT N. KHAFFER;DZHEJMS LARRIK;EHNDR'JU R. MENDELSON
分类号 A61K38/10;A61K39/00;A61P3/04;A61P3/10;A61P5/06;A61P9/00 主分类号 A61K38/10
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