METHOD OF OBTAINING N', N'-BIS{[ALKYL(PHENYL)SULFANYL]METHYL} ARYL HYDRAZIDES

摘要

FIELD: chemistry.SUBSTANCE: invention relates to method of obtaining N', N'-bis{[alkyl(phenyl)sulfanylmethyl]} aryl hydrazides of general formula (1)R=n-Pentyl, 1-Pr, Ph. Essence of method consists in interaction of aryl hydrazides of general formula ArC(O)NHNHwith N,N-dimethyl-N-{[alkyl(benzyl)sulfanyl]methyl}-amines of general formula MeN-CH-SR in presence of catalyst crystallohydrate of samarium nitrate Sm(NO)·6HO at temperature 75-85°C and atmospheric pressure in mixture of solvents chloroform-ethyl alcohol (1:1 volume) for 22-26 h.EFFECT: elaborated is novel method of obtaining claimed compounds, which can be applied as novel modified pharmacologically active medications.1 ex, 1 tbl