发明名称 Method for production of N-carboxy amino acid anhydride and amino acid carbamate compound
摘要 A method for production of an N-carboxy amino acid anhydride with efficiency is provided. The method for production of an N-carboxy amino acid anhydride includes a step of reaction of an amino acid organic salt compound with a carbonic acid diester.
申请公布号 US8748650(B2) 申请公布日期 2014.06.10
申请号 US200913060391 申请日期 2009.08.26
申请人 JSR Corporation 发明人 Endo Takeshi;Koga Koichi;Sudo Atsushi
分类号 C07C205/00 主分类号 C07C205/00
代理机构 代理人
主权项 1. A method for production of an N-carboxy amino acid anhydride, comprising reacting an amino acid organic salt compound with a carbonic acid diester, wherein the amino acid organic salt compound is represented by formula (1): wherein AX+ represents an organic onium ion and Y represents an optionally substituted divalent hydrocarbon group, and wherein the carbonic acid diester is a compound represented by formula (2): wherein R4 and R5 each independently represent an aryl group which may have substituent(s), wherein the substituent(s) are selected from the group consisting of a nitro group, halogen atoms, a perfluoroalkyl group, a perchloroalkyl group, an ester group, an acetyl group, a cyano group and a benzoyl group.
地址 Tokyo JP