发明名称 ETHANOL OR 1,2-ETHANEDIOL CYCLOHEXYL ANTIBIOTIC DERIVATIVES
摘要 The invention relates to antibiotic ethanol or 1,2-ethanediol cyclohexyl derivatives of formula (I) wherein R1 represents (C1-C4)alkoxy; one or two of U, V, W and X represent(s) N and the remaining represent each independently CH or, in the case of V or X, may also represent CRa; Ra represents halogen; R2 represents H or OH; A represents CH2, CO, CH2CH=CH or COCH=CH; D represents a phenyl group optionally substituted one or two times by halogen atoms, or D represents a group of the formula (II) in which Q is oxygen or sulphur; and to salts of these derivatives of formula (I).
申请公布号 CA2635205(C) 申请公布日期 2014.06.10
申请号 CA20072635205 申请日期 2007.02.14
申请人 ACTELION PHARMACEUTICALS LTD 发明人 HUBSCHWERLEN, CHRISTIAN;SURIVET, JEAN-PHILIPPE;ZUMBRUNN-ACKLIN, CORNELIA
分类号 C07D498/04;A61K31/4375;A61P31/04;C07D241/44;C07D471/04;C07D513/04 主分类号 C07D498/04
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