Process of making β-hydroxyamino compounds

摘要

The present application relates to molecules comprising one or more beta-hydroxyamine moieties, for example, aminosilicones and compositions such as consumer products comprising such molecules, as well as processes for making and using such molecules and such compositions. The aforementioned process is safer, more efficient and thus more economical. Thus, the aforementioned moleculers may be more widely used.

主权项

1. A process of making one or more molecules comprising one or more beta-hydroxyamine moieties said process comprising:
a) combining one or more molecules comprising one or more primary and/or secondary amine moieties, said one or more molecules comprising an amino silicone, with one or more molecules comprising one or more epoxide moieties and a catalyst comprising a protic solvent, said protic solvent:
(i) having a hydroxyl equivalents of at least 0.007 equivalents per gram; and(ii) comprising at least two hydroxyl moieties per protic solvent molecule, and solubility of at least 0.2% by weight of protic solvent in the mixture at the conditions of the reaction, to form a first mixture; b) heating said first mixture to a temperature of from about 20° C. to about 200° C., and maintaining said temperature for a time of from about 10 seconds to about 48 hours, to form a composition comprising one or more molecules comprising one or more beta-hydroxyamine moieties; and c) optionally purifying said composition comprising one or more molecules comprising one or more beta-hydroxyamine moieties.