Methods for treating ovarian cancer by inhibiting fatty acid binding proteins

摘要

The present invention concerns methods and compositions for the inhibition or reduction of the primary tumor and metastasis by inhibition of fatty acid binding proteins.

主权项

1. A method of inhibiting ovarian cancer comprising administering to a subject having or suspected of having cancer an effective amount of a fatty acid binding protein (FABP) inhibitor, wherein the FABP inhibitor is a carbazole butanoic acid, aryl sulfonamide, sulfonylthiophene, 4-hydroxypyrimidine, 2,3-dimethylindole, benzoylbenzene, biphenyl-alkanoic acid, 2-oxazole-alkanoic acid, tetrahydropyrimidone, pyridone, pyrazinone, aryl carboxylic acid, tetrazole, triazolopyrimidinone, indole, or BMS480404.