Method for manufacturing a microfluidic chip, and related chip and plate

摘要

The invention relates to a method for manufacturing a microfluidic chip, wherein said method comprises the steps of: providing a plate combined with a layer of inorganic silica gel of formula: (HsiO3/2)2n where n is an integer, and providing a lid; chemically activating the layer of silica gel and the lid, in order to make the layer of gel and the lid hydrophilic; mechanically combining the layer of gel and the lid to form a chip, such that the layer of gel forms an intermediate layer between the plate and the lid; annealing the chip, such that the layer of silica gel transforms into an intermediate layer made up of a SiO2 matrix for rigidly securing the plate to the lid. The invention also relates to a related chip and plate.

主权项

1. A production process for a microfluidic chip, wherein it comprises the steps of:
providing a glass plate connected to a layer of gel of inorganic silica of formula:
(HSiO3/2)2n where n is a natural whole number greater than or equal to 1, and providing a glass cap; chemical activation of the layer of silica gel and of the cap to make the layer of gel and the cap hydrophilic; mechanical association of the layer of gel and of the cap to form a chip such that the layer of gel forms an intermediate layer between the plate and the cap; annealing of the chip such that the layer of silica gel is transformed into an intermediate layer formed by an Si02 connecting matrix of the plate and of the cap.