发明名称 |
<i>Staphylococcus aureus </i>surface protein SA1789 and protective vaccine based thereon |
摘要 |
The novel protein SA1789 from Staphylococcus aureus is provided as well as nucleic acid and nucleic acid sequence homologues encoding this protein. Also provided is a composition, particularly a S. aureus vaccine, comprising SA1789 protein or a fragment or derivative thereof capable of generating an immune response that leads to the killing and clearance of S. aureus. |
申请公布号 |
US8747858(B2) |
申请公布日期 |
2014.06.10 |
申请号 |
US201113809736 |
申请日期 |
2011.07.08 |
申请人 |
Merck Sharp & Dohme Corp. |
发明人 |
McNeely Tessie B.;Fan Hongxia;Miller Mark Andrew |
分类号 |
C07K14/195 |
主分类号 |
C07K14/195 |
代理机构 |
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代理人 |
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主权项 |
1. An isolated polypeptide consisting of the amino acid sequence set forth in SEQ ID NO: 2 or the amino acid sequence set forth in SEQ ID NO:2 with an additional N-terminal methionine.
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地址 |
Rahway NJ US |