发明名称 |
Immunogenic epitopes of NGEP antigen |
摘要 |
The invention provides a peptide comprising a human cytolytic T lymphocyte (CTL) epitope from the human tumor-associated antigen (TAA) New Gene Expressed in Prostate (NGEP), which can be used in vaccine prevention or therapy of prostate cancer, as well as a nucleic acid encoding the peptide, a vector comprising the nucleic acid, a cell comprising the peptide, nucleic acid, or vector, and compositions thereof. |
申请公布号 |
US8748390(B2) |
申请公布日期 |
2014.06.10 |
申请号 |
US201013265490 |
申请日期 |
2010.04.19 |
申请人 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
发明人 |
Schlom Jeffrey;Tsang Kwong-Yok;Pastan Ira |
分类号 |
A61K38/08;A61K39/00;C07K7/06 |
主分类号 |
A61K38/08 |
代理机构 |
|
代理人 |
|
主权项 |
1. An immunogenic epitope having no more than 20 amino acid residues and comprising GLFDEYLEMV (SEQ ID NO:1), wherein the immunogenic epitope binds to HLA-A2.
|
地址 |
Washington DC US |