| 发明名称 |
RESORCYLIC ACID LACTONE COMPOUNDS |
| 摘要 |
Disclosed are a novel resorcyclic acid lactone compound with inhibitory activity against protein kinases, a pharmaceutically acceptable salt thereof, a method for the synthesis thereof, and a pharmaceutical composition for the treatment and prevention of various cancer diseases comprising the same as an active ingredient. The novel resorcyclic acid lactone compound is useful as a therapeutic for cancer diseases, especially blood cancer, inter alia, acute myeloid leukemia (AML). |
| 申请公布号 |
US2014155635(A1) |
申请公布日期 |
2014.06.05 |
| 申请号 |
US201314066053 |
申请日期 |
2013.10.29 |
| 申请人 |
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY |
发明人 |
SIM Tae Bo;Yoon Ho Jong;Kim Ji Nyeo |
| 分类号 |
C07D313/00;C07D493/08;C07D317/30;C07D407/10;C07D319/08;C07D317/32 |
主分类号 |
C07D313/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound, selected from among a resorcyclic acid lactone compound represented by the following Chemical Formula F, and a pharmaceutically acceptable salt thereof:(wherein R1, R2, R3, and R4 independently represent a hydrogen atom or C1˜C10 alkyl).
|
| 地址 |
Seoul KR |
