METHOD OF PAINTING MICROVESICLES

摘要

The present invention relates to a method to modify and/or to isolate exosomes and other naturally occurring plasma membrane derived micro vesicles, by incubation with a reactant, consisting of at least a membrane anchor domain or moiety and a hydrophilic functional domain or moiety. The invention also relates to modification using the same of artificially-prepared lipid bilayer vesicles called liposomes (composed of natural phospholipids) and non-biological or "synthetic" block copolymer membrane mimics which also form vesicles in aqueous solution called polymersomes.