发明名称 |
NOVEL PHARMACEUTICAL COMPOSITION |
摘要 |
Disclosed are novel pharmaceutical compositions containing N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide dimethyl sulfoxide solvate, methods of using the compositions in therapy and processes for preparing the same. |
申请公布号 |
US2014154316(A1) |
申请公布日期 |
2014.06.05 |
申请号 |
US201314103092 |
申请日期 |
2013.12.11 |
申请人 |
GlaxoSmithKline Intellectual Property (No.2) Limited |
发明人 |
DeMARINI Douglas J.;Henriquez Francisco;Le Ngocdiep T.;Wang Lihong |
分类号 |
A61K9/28;A61K31/519 |
主分类号 |
A61K9/28 |
代理机构 |
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代理人 |
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主权项 |
1. A pharmaceutical tablet comprising:
a) an amount of a drug, which is N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide dimethyl sulfoxide solvate, selected from: about 0.5635 mg, about 1.127 mg, and about 2.254 mg; wherein, b) the drug particles are micronized.
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地址 |
Brentford GB |