发明名称 NOVEL PHARMACEUTICAL COMPOSITION
摘要 Disclosed are novel pharmaceutical compositions containing N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide dimethyl sulfoxide solvate, methods of using the compositions in therapy and processes for preparing the same.
申请公布号 US2014154316(A1) 申请公布日期 2014.06.05
申请号 US201314103092 申请日期 2013.12.11
申请人 GlaxoSmithKline Intellectual Property (No.2) Limited 发明人 DeMARINI Douglas J.;Henriquez Francisco;Le Ngocdiep T.;Wang Lihong
分类号 A61K9/28;A61K31/519 主分类号 A61K9/28
代理机构 代理人
主权项 1. A pharmaceutical tablet comprising: a) an amount of a drug, which is N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide dimethyl sulfoxide solvate, selected from: about 0.5635 mg, about 1.127 mg, and about 2.254 mg; wherein, b) the drug particles are micronized.
地址 Brentford GB