发明名称 |
BIODEGRADABLE MICROBEAD COMPRISING ANIONIC POLYMER FOR IMPROVING ADSORPTIVE POWER TO ANTICANCER DRUGS, AND METHOD FOR PREPARING SAME |
摘要 |
The present invention relates to a biodegradable microbead having improved adsorptive power to anticancer drugs, to a method for preparing same, and to a method for treating cancer using same. According to the present invention, a rigid bead having excellent adsorptive power to anticancer drugs can be prepared through cross-linking and an amide bond between an albumin and an anionic polymer. Also, the microbead of the present invention is prepared by a biocompatible and biodegradable polymer so as to be safe when applied to the human body. Further, the microbead of the present invention can effectively inhibit the growth of a tumor by effectively blocking a blood vessel which supplies nutrients to a liver tumor, while continuously releasing anticancer drugs which are adsorbed into the surface of the bead. Thus, the present invention can be usefully applied to a chemoembolization of liver cancer. |
申请公布号 |
WO2014084530(A1) |
申请公布日期 |
2014.06.05 |
申请号 |
WO2013KR10420 |
申请日期 |
2013.11.15 |
申请人 |
UTAH-INHA DDS & ADVANCED THERAPEUTICS RESEARCH CENTER |
发明人 |
KIM, SE YOON;LEE, DON HAENG;YANG, SU-GEUN |
分类号 |
A61K9/16;A61K47/30;A61P35/00 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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地址 |
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