| 发明名称 |
BTK INHIBITORS |
| 摘要 |
The present invention provides 6-5 membered fused pyridine ring compounds according to Formula I or pharmaceutically acceptable salts thereof.
or a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of 6-5 membered fused pyridine ring compounds in the treatment of Bruton's Tyrosine Kinase (Btk) mediated disorders. |
| 申请公布号 |
KR20140068020(A) |
申请公布日期 |
2014.06.05 |
| 申请号 |
KR20147003924 |
申请日期 |
2012.07.19 |
| 申请人 |
MERCK SHARP & DOHME CORP.;MERCK SHARP & DOHME B.V. |
发明人 |
DE MAN ADRIANUS P.A.;STERRENBURG JAN GERARD;RAAIJMAKERS HANS C.A.;KAPTEIN ALLARD;OUBRIE ARTHUR;REWINKEL JOHANNES B.M.;JANS CHRISTIAAN G.J.M.;WIJKMANS JACOBUS C.H.M;BARF TJEERD A.;COOPER ALAN B.;KIM RONALD M.;BOGA SOBHANA BABU;ZHU HUGH Y.;GAO XIAOLEI;YAO XIN;ANAND RAJAN;WU HAO;LIU SHILAN;YANG CHUNDAO;ALHASSAN ABDUL BASIT;WANG JAMES;YU YOUNONG;LIU JIAN;VACCARO HENRY M. |
| 分类号 |
C07D487/04;A61K31/437;A61K31/4985;A61P3/10;C07D401/10;C07D403/10 |
主分类号 |
C07D487/04 |
| 代理机构 |
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