METHODS OF DETERMINING STABILIZATION COMPOUNDS FOR PREDICTIVE BIOMARKERS

摘要

Methods of determining stabilization compounds for predictive biomarkers. According to at least one embodiment of a method of the present disclosure, the method comprises introducing a diagnostic marker and a stabilization agent to a detection platform, mixing the diagnostic marker and stabilization agent, and determining their binding characteristics. Additionally, the method may further comprise generating a report based on the binding characteristics and delivering the report to a recipient.

主权项

1. A method for analyzing stabilization agents, the method comprising the steps of:
introducing a diagnostic marker into each of a plurality of detection sites of a detection platform, the detection platform comprising:
the plurality of detection sites each capable of receiving a diagnostic marker, a stabilization agent, and a detection agent;a detection device capable of determining a binding characteristic between the detection agent and the diagnostic marker in the detection sites;a computer database capable of receiving a plurality of binding characteristics, the plurality of binding characteristics comprising at least one binding property of a diagnostic marker to a detection agent;a processor operably coupled to the computer database and the detection device, the processor having and executing a software program operational to:
determine the binding characteristic of the detection agent to the diagnostic marker in each of the plurality of detection sites;compare the binding characteristic among each of the plurality of detection sites to order the level of effect of the stabilizing agents assayed on the binding characteristic between the detection agent and the diagnostic agent;generate a binding record using the compared binding characteristics; anddeliver the binding record to a recipient; introducing the stabilization agent to each of the plurality of detection sites containing the diagnostic marker; combining the detection agent with the stabilization agent and diagnostic marker in the detection sites; comparing the binding characteristic with the processor among each of the plurality of detection sites to order the level of effect of the stabilizing agents assayed on the binding characteristic between the detection agent and the diagnostic agent; generating a binding report using the compared binding characteristics; and delivering the binding report to a recipient.