发明名称 |
HBV POLYMERASE MUTANTS. |
摘要 |
The present invention relates to polymerase HBV mutant polypeptides comprising a mutated polymerase domain which is functionally disrupted for polymerase activity and fusion proteins comprising such polymerase mutant polypeptide. The present invention also relates to a nucleic acid molecule and an expression vector for expressing said polymerase mutant polypeptide as well as a composition which can be used for eliciting an immune response to HBV with the goal of providing a protective or therapeutic effect against HBV infection. |
申请公布号 |
MX2014000488(A) |
申请公布日期 |
2014.06.05 |
申请号 |
MX20140000488 |
申请日期 |
2012.07.12 |
申请人 |
TRANSGENE SA |
发明人 |
SILVESTRE, NATHALIE;MARTIN, PERRINE;MARCHAND, JEAN-BAPTISTE |
分类号 |
C12N9/22;A61K38/16;A61K39/29;A61P31/12;C07K14/02;C12N5/10 |
主分类号 |
C12N9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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