发明名称 |
HYDROXYTYROSOL AND OLEUROPEIN COMPOSITIONS FOR INDUCTION OF DNA DAMAGE, CELL DEATH AND LSD1 INHIBITION |
摘要 |
Compositions comprising hydroxytyrosol-containing formulations and treatment regiments comprising hydroxytyrosol and/or oleuropein and chemotherapeutic agents are disclosed. Compositions and/or regiments may optionally include the administration of vitamins, minerals, and anti-oxidants. Methods for using these compositions and treatment regimens for treating subjects for diseases, such as a malignancy, and for inducing or enhancing angiogenesis, treating or preventing oxidative stress, for treating or preventing high glucose-induced dysfunction, treating or preventing chemotherapy-induced dysfunction, and for improving cell viability are provided. Various methods for use of the hydroxytyrosol compositions for inhibition of lysine specific demethylase 1 (LSD1) in various cancers are also provided. |
申请公布号 |
WO2014085613(A1) |
申请公布日期 |
2014.06.05 |
申请号 |
WO2013US72276 |
申请日期 |
2013.11.27 |
申请人 |
MCCORD, DARLENE E.;KARAGIANNIS, THOMAS |
发明人 |
MCCORD, DARLENE E.;KARAGIANNIS, THOMAS |
分类号 |
A61K31/05;A61K31/045;A61P35/00 |
主分类号 |
A61K31/05 |
代理机构 |
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代理人 |
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地址 |
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