发明名称 |
PROTOZOAN PROTEIN PERTAINING TO PLASMODIUM INFECTION IN LIVER STAGE |
摘要 |
<p>The present invention addresses the problem of identifying a protein essential for plasmodium in a liver-infection stage to proceed to the next stage, pro viding a test method for searching for a compound obstructing this prote in, and providing a compound for hindering infection with plasmodium by obstructing the protein. The objective is achieved by a method of testing a subst ance for hindering infection with plasmodium, the test method being characterized in that an evaluation is made of whether or not merozoite formation in a liver stage of infection with plasmodium is obstructed by restraining action of LS-specific protein 2 (LISP2) in which plasmodium is specifically ex pressed in host cells in the middle to the latter period of the liver stage.</p> |
申请公布号 |
WO2014084333(A1) |
申请公布日期 |
2014.06.05 |
申请号 |
WO2013JP82139 |
申请日期 |
2013.11.29 |
申请人 |
MIE UNIVERSITY |
发明人 |
YUDA, MASAO;IWANAGA, SHIROH;KANEKO, IZUMI |
分类号 |
C12Q1/02;A61K39/002;A61P33/06;C12N15/09;G01N33/15;G01N33/50 |
主分类号 |
C12Q1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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