| 发明名称 |
N,N-SUBSTITUTED GUANIDINE COMPOUND |
| 摘要 |
The invention is directed to a N,N-substituted guanidine compound or a salt or solvate thereof according to formula (1), R1RNC(NH)NR2R3, wherein R1 is methyl and R2 is hydrogen. R3 is a organic group comprising a halogen and thiomethyl substituted phenyl group. R is an organic group comprising a substituted aryl group Z wherein the substituent group is —Y—R4, wherein Y is a heteroatom chosen from the group consisting of O, S and N and R4 is a fluorinated organic group. |
| 申请公布号 |
US2014154182(A1) |
申请公布日期 |
2014.06.05 |
| 申请号 |
US201214122691 |
申请日期 |
2012.05.30 |
| 申请人 |
Klein Pieter Jacob;Metaxas Athansios;Windhorst Albert Dirk;Christiaans Johannes Antonius Maria;van Berckel Bart Nicolaas Maria |
发明人 |
Klein Pieter Jacob;Metaxas Athansios;Windhorst Albert Dirk;Christiaans Johannes Antonius Maria;van Berckel Bart Nicolaas Maria |
| 分类号 |
C07C279/18;C07C277/08;A61K51/04 |
主分类号 |
C07C279/18 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A N,N-substituted guanidine compound or a salt or solvate thereof according to formula (1) wherein R4 is a fluorinated organic group, Y is O, S or N, Z is a substituted aryl group, R1 is methyl, R2 is hydrogen, R5 is Cl or Br and R6 is a thiomethyl group.
|
| 地址 |
Amsterdam NL |
