发明名称 Phenyl derivatives or pharmaceutically acceptable salts thereof, preparation method thereof, and composition for the prevention, improvement and treatment of vascular endothelial cell related-diseases or diabetes mellitus containing the same as an active ingredient
摘要 PURPOSE: A phenyl derivative is provided to effectively control grape sugar utilization, to effectively suppress the generation of a final diabetic oxide which is a factor causing diabetic complications, and to prevent and treat endothelial cell related-diseases or diabetes mellitus. CONSTITUTION: A phenyl derivative is represented by chemical formula 1. In chemical formula 1, each of R^1, R^2, and R^3 is hydrogen, a C1-6 linear or branched alkyl group, an unsubstituted or C1-4 linear or branched alkyl-substituted amino, a heterocycloalkyl-substituted C1-4 linear or branched alkyl group, an amino linear or branched C1-4 alkyl carbonyl group, a C1-4 linear or branched alkylcarbonyl, a heterocycloalkyl-substituted carbonyl group, a C5-C6 arylcarbonyl group, a C1-4 linear or branched alkyloxycarbonyl, a C1-4 linear or branched alkyloxycarbonyl, a C1-4 linear or branched alkylcarbonyl group, a phosphono group, a glucosyl group, a galactosyl group, a rhamnosyl, a xylosyl, an arabinosyl, or a glucuronic acid.
申请公布号 KR101403488(B1) 申请公布日期 2014.06.05
申请号 KR20120064882 申请日期 2012.06.18
申请人 发明人
分类号 A61K31/191;A61P3/10;C07C63/331;C07D265/30 主分类号 A61K31/191
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