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1. A compound of formula (I): or a salt thereof, wherein: R1 is halo, CF3, C1-C6-alkyl, isopropenyl, (C2-C6-alkylene) C3-C6-cycloalkyl, C1-C6-alkoxy, or cyano; in R2, when p is other than 0, each R2 is independently F, Cl, CF3, methyl, methoxy, CH2CF3, —(X)q—C1-C4-alkylene-R4, —(X—C1-C4-alkylene)q-NR5—C(O)—R6, —(X—C1-C4-alkylene)q-(NR5)q—SOx—R7, —(X—C1-C4-alkylene)q-Y—N(R8)2, a 5- to 6-membered heterocycloalkyl-(R9)q group, or a 5- to 6-membered heteroaryl-(R10)r group; each R3 is independently H, C3-C6-cycloalkyl, C1-C6-alkyl, C1-C6alkoxy, C1-C6-alkylene-R4, —N(R)2, O—C1-C6-alkylene-R4, or, the R3 groups, together with Z form a 5- to 6-membered cycloalkyl or cycloheteroalkyl where the hetero atom is N or O and ring is optionally substituted on a carbon or heteroatom by methyl, C1-C4-alkylene-R4, or C3-C6-cycloalkyl; R4 is H, -(Q)q-N(R8)2, OH, SH, C1-C6-alkoxy, C1-C6-thioalkyl, or a 5- to 6-membered heterocycloalkyl-(R9)q group; R5 is H or C1-C6-alkyl; R6 is H, C1-C6-alkyl, C1-C6-alkoxy, N(R8)2, or a 5- to 6-membered heteroaryl-(R10)r group; R7 is C1-C6-alkyl, phenyl-(R9)q, or 5- to 6-membered heteroaryl-(R10)r R8 is independently H, C1-C6-alkyl, —O—C1-C6-alkyl or, together with the nitrogen atom to which they are attached, form a 5- or 6-membered heterocycloalkyl group; R9 is H, C1-C6-alkyl, C1-C6-alkoxy, -(Q)q-N(R8)2, -Q-C1-C6-alkyl, —C1-C6alkylR4, or 5- to 6-membered heterocycloalkyl; R10 is H, C1-C6-alkyl, C1-C6-alkoxy, or -Q-C2-C6-alkyl; R11 is C1-C6-alkyl, CF3, —CH2CF3, -(Q)q-C1-C4-alkylene-R4, -Q-N(R8)2, phenyl-(R5)s, a 5- to 6-membered heterocycloalkyl-(R9)q group, or a 5- to 6-membered heteroaryl-(R10)r group; R12 is H, C1-C6-alkyl, F, Cl, CF3, OH, CN, nitro, COOH, —COO—C1-C6-alkyl, —C1-C6-alkylOH, —C1-C6-alkylN(R8)2, —Y—N(R8)2, C3-C6-cycloalkyl-R14, —(X)q—C1-C6-alkylene-R4, —(X—C1-C6-alkylene)q-NR5—C(O)—R6, —(X—C1-C6-alkylene)q-(NR5)q—SOx—R7, —(X—C1-C6-alkylene)q-Y—N(R8)2, heterocycloalkyl-(R9)q, heteroaryl-(R8)r, or phenyl-(R15)s; R13 is H, F, Cl, C1-C6-alkyl, or C3-C6-cycloalkyl; or R12 and R13, together with the carbon atoms to which they are attached, form a fused 5- or 6-membered carbocycloalkyl or heterocycloralkyl group; R14 is independently H, C1-C6-alkyl. —NR5—SO2—R7, —Y—N(R8)2, or —(X)q—C1-C6-alkylene-R4; each R15 is independently F, Cl, CF3, C1-C3-alkyl, or C1-C3-alkoxy; p is 0, 1, 2, or 3; q is 0 or 1; r is 0, 1, or 2; s is 0, 1, 2, or 3; x is 1 or 2; Q is —C(O)—, —S(O)—, or —SO2—; X is NR5, O, S, —S(O)—, or —SO2—; Y is a bond, SO2, or C(O); and Z is N or CR5.
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