主权项 |
1. Compound of formula (I)in which:
R1 represent a —(CH2)4C(O)OH group; n represents 0 or 1; m represents an integer ranging from 0 to 8; L1 represents a —C(O)—; —C(O)O— or —S(O)2— group; R2 represents:
a carbocycle group with 5, 6 or 7 members, saturated, partially unsaturated or aromatic, substituted or non-substituted;a polycarbocycle group with 8 to 14 members, saturated, partially unsaturated or aromatic, substituted or non-substituted;a heterocycle group with 5, 6 or 7 members, substituted or non-substituted, saturated, partially unsaturated or aromatic, comprising 1, 2 or 3 heteroatoms, identical or different;a polyheterocycle group with 8 to 14 members, substituted or non-substituted, saturated, partially unsaturated or aromatic, comprising 1, 2 or 3 heteroatoms identical or different;a -L2-carbocycle group, the carbocycle being in 5, 6 or 7 members, saturated, partially unsaturated or aromatic, substituted or non-substituted;a -L2-polycarbocycle, the polycarbocycle being in 8 to 14 members, saturated, partially unsaturated or aromatic, substituted or non-substituted;a -L2-heterocycle group, the heterocycle being in 5, 6 or 7 members, substituted or non-substituted, saturated, partially unsaturated or aromatic and comprising 1, 2 or 3 heteroatoms, identical or different;a -L2-polyheterocycle group, the polyheterocycle being in 8 to 14 members, substituted or non-substituted, saturated, partially unsaturated or aromatic and comprising 1, 2 or 3 hetero atoms, identical or different; ora hydrocarbon group, linear or branched, C1 to C5; L2 represents an alkyl, linear or branched, C1 to C5; R3, identical or different, represent:
an alkyl, linear or branched, C1 to C5;a -L2-carbocycle group, the carbocycle being in 5, 6 or 7 members, saturated, partially unsaturated or aromatic, substituted or non-substituted;a -L2-polycarbocycle, the polycarbocycle being in 8 to 14 members, saturated, partially unsaturated or aromatic, substituted or non-substituted;a -L2-heterocycle group, the heterocycle being in 5, 6 or 7 members, substituted or non- substituted, saturated, partially unsaturated or aromatic and comprising 1, 2 or 3 heteroatoms, identical or different, in particular chosen from nitrogen, oxygen or sulphur; ora -L2-polyheterocycle group, the polyheterocycle being in 8 to 14 members, substituted or non-substituted, saturated, partially unsaturated or aromatic and comprising 1, 2 or 3 heteroatoms, identical or different, in particular chosen from nitrogen, oxygen or sulphur; isomers, enantiomers and diastereoisomers thereof and the addition salts thereof with pharmaceutically acceptable bases or acids.
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