Modulation of Thymosin Beta-4 in Skin

摘要

Methods for preventing, ameliorating, or reducing dermatological signs of aging are provided which employ active agents, other than a retinoid, that stimulate thymosin beta-4 expression in the skin. Also provided are methods for screening for substances which stimulate thymosin beta-4 expression levels and the methods of using active agents identified by the screening protocol in the treatment of skin.

主权项

1. A method for improving the aesthetic appearance of human skin comprising topically applying to an area of the skin in need thereof an effective amount of an active agent, other than a retinoid, that stimulates human thymosin beta-4 expression, for a time sufficient to improve the aesthetic appearance of said human skin.