| 发明名称 |
NOVEL CHEMOKINE BINDING POLYPEPTIDES CAPABLE OF INHIBITING THE COURSE OF AUTOIMMUNITY, INFLAMMATION AND CANCER |
| 摘要 |
Novel polypeptides comprising a chemokine-binding peptide and an Fc fragment are disclosed. The polypeptides are capable of binding to certain chemokines so as to modulate their activity. These polypeptides can be used to modulate in vivo chemokine-dependent processes such as inflammation and autoimmunity, and to treat associated conditions. |
| 申请公布号 |
US2014154249(A1) |
申请公布日期 |
2014.06.05 |
| 申请号 |
US201414178301 |
申请日期 |
2014.02.12 |
| 申请人 |
Biokine Therapeutics Ltd. |
发明人 |
ABRAHAM Michal;Eizenberg Orly;Peled Amnon |
| 分类号 |
C07K16/24 |
主分类号 |
C07K16/24 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An isolated polypeptide comprising at least one chemokine-binding peptide attached to an Fc domain or a fragment of said Fc domain, wherein said chemokine-binding peptide has the amino acid sequence as set forth in SEQ ID NO: 76.
|
| 地址 |
Nes Ziona IL |
